Figure 7-1: Integration by site-specific recombination, between the attP site of the phage and the attB site of the host. The two circular molecules form a cointegrate, with junction points attL (left prophage end) and attR (right prophage end). Integration is carried out by a phage-coded protein, integrase. In many phages (including λ), the reverse reaction (excision) frequently requires a second phage-coded protein, excisonase. Host proteins contributing to the reaction are not shown. (for better image quality, click here for tif image, which may be quite large; may also require screen refreshing plus special software to view; or view larger tif in separate window)Figure 7-1, Figure 7-2, Figure 7-3, Figure 7-4, Figure 7-5, Figure 7-6, Figure 7-7, Figure 7-8
return to Campbell, General Aspects of Lysogeny