Figure 8-4: OR:OL interaction. One possible set of interactions between CI bound at OL and OR. On the left is shown an interaction involving dimers bound at each of four sites. The intervening 2.4 kb form a loop (indicated by the dashed arc). This structure would form from a non-looped structure (not shown) by cooperative interactions between tetramers at each site. Both PL and PR are presumed to be repressed in this structure, as they would be in the absence of looping when CI binds. On the right is a complex containing additional dimers bound to OR3 and OL3; in this complex, PRM is repressed. Other complexes may also form; for instance, the OL region might be inverted from the orientation shown. (for better image quality, click here for tif image, which may be quite large; may also require screen refreshing plus special software to view; or view larger tif in separate window)Figure 8-1, Figure 8-2, Figure 8-3, Figure 8-4
return to Little, Gene Regulatory Circuitry of Phage λ