Figure 10-9: Single-gene lysis systems in ssDNA and ssRNA phages. Lysis genes are shaded. Top: Map of MS2, the prototype group I ssRNA phage, with the L sequence displayed above the map. L sequences from the group I phage fr (4), the group II phage GA (62), and the Acinetobacter phage AP205 (70) are arrayed above MS2 L for comparison. Middle: Map of Qb, the prototype group III ssRNA phage (106). The regions of close sequence similarity between Qb A₂ and MS2 A are hatched, and the locations of the por mutations, selected for plaque-formation on a rat host, are indicated by stars (15) (I.-N. Wang and R. Young, unpublished). Bottom: Map of the single-stranded circular DNA phage fX174, shown linearized at the start of the A gene. The sequence of the E lysis protein is displayed below the map, along with an alignment of the ortholog E proteins from the related phages (top to bottom) G4, a3 and S13 (48, 122). (for better image quality, click here for tif image, which may be quite large; may also require screen refreshing plus special software to view; or view larger tif in separate window)

Figure 10-1, Figure 10-2, Figure 10-3, Figure 10-4, Figure 10-5, Figure 10-6, Figure 10-7, Figure 10-8, Figure 10-9, Figure 10-10

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