Figure 15-8: Evolution of the stabilized coat-protein initiator-hairpin shown as mutant 45.0 in the center. Black boxes in 45.0 are man-made mutations. Black boxes in the pseudorevertants 45.1 - 45.8 are suppressor mutations selected by nature upon passaging the mutant phage. Numbers at arrows (e.g. 4x) show the number of plaques containing that specific suppressor mutation. All pseudorevertants have evolved an initiator hairpin that has a thermodynamic stability close to wild type (boxed at top). Taken from reference (58). (for better image quality, click here for tif image, which may be quite large; may also require screen refreshing plus special software to view; or view larger tif in separate window)

Figure 15-1, Figure 15-2 ( ab ), Figure 15-3, Figure 15-4, Figure 15-5, Figure 15-6, Figure 15-7, Figure 15-8, Figure 15-9 ( ab ), Figure 15-10, Figure 15-11, Figure 15-12, Figure 15-13,

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